A study of whether use of noninvasive coronary CT angiography (CCTA) can cut down on the use of invasive coronary angiography when making treatment decisions in patients who have undergone previous coronary artery bypass surgery (CABG) has shown mixed interim results.
The GREECE trial was aiming to show that doses of contrast and radiation were lower for the patients who received CCTA before invasive angiography, but the study showed that doses were actually higher in the combination imaging group. But this did not affect the main safety endpoint ― contrast-induced nephropathy ― for which rates were comparable between the two arms
