The transition from perimenopause to menopause is accompanied by a proatherogenic shift in lipids and other circulating metabolites that potentially predispose women to cardiovascular disease (CVD). Now, for the first time, a new prospective cohort study quantifies the link between hormonal shifts and these lipid changes.
However, hormone replacement therapy (HRT) somewhat mitigates the shift and may help protect menopausal women from some elevated CVD risk, the same study suggests.
