Research Recap

 
 
  • NASH in Diabetes: New Therapies on the Horizon With 'a host' of treatments in the pipeline, fatty liver disease no longer plays second fiddle to diabetes-related cardiovascular disease and chronic kidney disease, says researcher Gregory Nichols.
  • New Weapons Against Cardiorenal Syndrome Cardiovascular outcomes trials show beneficial effects of sodium-glucose cotransporter 2 inhibitors (SGLT2i) on both cardiovascular and renal outcomes, sparking renewed interest in cardiorenal syndrome.
  • Amputations in Diabetes Back on the Rise, but Why? After a steady decline in rates of amputation in patients with diabetes, a new study shows that rates are increasing, with few obvious explanations as to why.
  • SGLT2 Inhibitors: Is This the Start of a New Era? Gregory Nichols discusses exciting new clinical trial results demonstrating the benefits of SGLT2 inhibitors, as presented at the AHA 2018 Scientific Sessions.
  • Prevention of Type 2 Diabetes Highlighted at EASD 2018 Dietary changes and regular exercise are proven interventions that reduce the risk for type 2 diabetes, but with rates of obesity on the rise, other strategies may be required.
  • A Quick Planner for ADA ADA meeting veteran Gregory Nichols offers a guide to the upcoming ADA 78th Scientific Sessions and which sessions have sparked his interest.
  • Simple Tool Predicts 2-Year Diabetes Risk An operational question about allocating diabetes resources results in a simple algorithm that identifies the people at highest risk for developing diabetes.
  • Anatomy of a Research Project: From Idea to Publication Ever wonder how a medical study got its start? A researcher shares his personal journey.
  • What Comes After Metformin in Type 2 Diabetes? Choosing the right drug for the right patient can affect glycemic control and mortality outcomes.
  • In T2D, How Low Should BP Go? Should most patients with diabetes be on intensive blood pressure interventions?
  • Reducing CV Risk in Diabetes: 'When' and 'How' Matter Reducing cardiovascular risk with glycemic control may depend on when and how it is achieved.
  • Entering Adulthood With Diabetes Whether it's type 1 or 2, diabetes in youth requires early and aggressive management. Dr Nichols reviews new research on disease course and challenges associated with transition to adult care.
  • Assess Patients With Diabetes for Sleep Quality Poor sleep may have profound effects on people with diabetes, as well as risk for diabetes.
  • Paradigm Change in Diabetes Care: Prompt, Intensive Therapy Gregory Nichols links the findings of two important diabetes trials to suggest that earlier and more effective therapy could save lives and prevent complications.
  • Fitness, Fatness, and Risk for Diabetes What role do body weight and fitness level play in the risk for prediabetes and diabetes? And is it too late to reverse these trends?
  • Is A1c Variability a Useful Measure in Diabetes? Fluctuations in glycated hemoglobin levels have been suggested as an independent risk factor for diabetic complications, but new studies cast doubts on that concept.
  • Personalizing Diabetes Treatment Targets When patients respond to treatment, how often do providers deintensify their treatment? A new algorithm may simplify and personalize that decision.
  • After Metformin, What Comes Next? Empagliflozin? Are we any closer to answering the question of what drug should be added when metformin monotherapy needs a boost? Two studies shed some light.
  • Type 2 Diabetes Can Be Prevented: Why Are We Waiting? Despite the evidence supporting benefit, clinicians have been slow to recommend either healthy lifestyle changes or metformin for diabetes prevention.
  • Skip the Weigh-in for Type 2 Diabetes Patients? Does fitness explain the 'obesity paradox'? Dr Nichols examines two new studies that may add to our understanding of this phenomenon.