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A Key Indicator in Late-Onset Alzheimer Disease?
Dr Alan Jacobs shares results of a 'big data' analysis of biomarkers that may one day have value as therapeutic interventions.
Experts And Viewpoints, November 28, 2016
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Nilotinib Shows Early Safety in Parkinson' Dementia
Dr Alan Jacobs details a small proof-of-concept study, the first to treat persons with advanced Parkinson's with a tyrosine kinase inhibitor.
Experts And Viewpoints, August 25, 2016
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Genetic Link Confirmed for Neurodegeneration and Metabolism
Dr Alan Jacobs details a new study with SORLA, a genetic risk factor for Alzheimer disease that is now linked to obesity.
Experts And Viewpoints, August 18, 2016
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A Downside to Smartphone Alerts
Dr Alan Jacobs discusses a study in college students which concluded that strategies should be taken to curtail our constant digital stimulation.
Experts And Viewpoints, August 12, 2016
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Does Menopause Mean More Migraines?
Dr Alan Jacobs reviews a study that determines whether migraine frequency increases in women during menopausal transition.
Experts And Viewpoints, July 08, 2016
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Do People Feel Pain While Sleepwalking?
Do sleepwalkers feel pain? Dr Alan Jacobs discusses new research exploring the question.
Experts And Viewpoints, July 01, 2016
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Targeting a Single Pathway to Treat Peripheral Neuropathy
Dr Alan Jacobs reviews the results of a recent study finding that overactivation of matrix-metalloproteinase-13 is a key mechanism underlying peripheral neuropathy.
Experts And Viewpoints, June 24, 2016
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Could Diet Improve Outcomes in Glioblastoma?
Dr Alan Jacobs discusses an experimental study evaluating a high-fat, low-carbohydrate diet in mice with glioblastoma.
Experts And Viewpoints, May 13, 2016
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The Neuroscience of Regulating Sleep Duration
Dr Alan Jacobs discusses a recent study finding that calcium-dependent hyperpolarization regulates sleep duration in mammals.
Experts And Viewpoints, May 06, 2016
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Immunotherapy in the Prevention of Alzheimer Disease
Dr Jacobs reviews the results of a recent study evaluating passive immunotherapy with encapsulated cell implants to target misfolded proteins in the prevention of Alzheimer disease.
Experts And Viewpoints, May 02, 2016
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Do Benzodiazepines Increase the Risk for Dementia?
A recent study finds that higher cumulative benzodiazepine use is not associated with risk for dementia or cognitive decline, explains Dr Alan Jacobs.
Experts And Viewpoints, April 22, 2016
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Cannabidiol for Treatment-Resistant Epilepsy
Dr Jacobs reviews the results of an open-label trial evaluating the safety and efficacy of cannabidiol in patients with treatment-resistant epilepsy.
Experts And Viewpoints, April 15, 2016
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A Potential Therapeutic Target in ALS and Dementia
Researchers have identified mutations that may be a key to understanding and treating some forms of neurodegeneration.
Experts And Viewpoints, March 15, 2016
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Can the MIND Diet Reduce Alzheimer's Risk?
Adhering to the MIND diet has been associated with a reduction in risk for Alzheimer disease and slowing of cognitive decline among aging adults.
Experts And Viewpoints, March 08, 2016
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Ghrelin Receptor Blockade and Food Behaviors
New preclinical data show that ghrelin may play an important role in food behaviors and that blocking these receptors may reduce food foraging, hoarding, and intake.
Experts And Viewpoints, March 01, 2016
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A New Map of the Hippocampus
Researchers have developed a new, detailed map of the hippocampus that may aid in future research to improve treatment for neurologic and psychiatric disorders.
Experts And Viewpoints, February 23, 2016
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A Possible Therapy for Menopausal Cognitive Decline
Menopausal women taking LDX showed significant improvements in organization and motivation for work, attention, and processing speed.
Experts And Viewpoints, February 09, 2016
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A New Drug Class for Migraine Prevention
Dr Jacobs discusses a new therapeutic class of agents for migraine prevention and some phase 2 results.
Experts And Viewpoints, January 20, 2016
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A Combo Therapy for Agitation in Alzheimer Disease
Dr Jacobs reviews the results of a preliminary trial evaluating dextromethorphan/quinidine for reducing symptoms of agitation in patients with Alzheimer disease.
Experts And Viewpoints, November 13, 2015
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Does Physical Activity Affect Cognition?
Dr Jacobs reviews the results of a study evaluating the relationship between aerobic exercise and cognitive outcomes.
Experts And Viewpoints, November 10, 2015
