Genomics Journal Articles

• Genetic Factors in Sofosbuvir Treatment for Chronic HCV Are there patient-specific genetic factors that might help predict HCV patients likely to fail sofosbuvir treatment?
  Liver International, May 23, 2022
• The Oncogenic Landscape of the IPF: A Narrative Review Recent advances have helped further our understanding of the link between idiopathic pulmonary fibrosis and lung cancer, contributing to improvements in diagnosis and treatment.
  Translational Lung Cancer Research, May 23, 2022
• MIS in Children After SARS-CoV-2 Vaccination Does COVID-19 vaccination play a role in the pathogenesis of multisystem inflammatory syndrome in children? This report helps further our understanding.
  Emerging Infectious Diseases, May 20, 2022
• Genetic and Environmental Scores for CRC Risk Stratification A newly developed risk prediction model that incorporates both genetic and environmental factors could lead to the earlier identification of patients at high risk for colorectal cancer.
  Journal of the National Cancer Institute, May 18, 2022
• Inflammation, Aging, and Cardiovascular Disease This review discusses recent advances regarding "inflamm-aging"; that is, age-dependent activation of inflammation and the pathways by which it influences the onset of cardiovascular disease.
  Journal of the American College of Cardiology, May 18, 2022
• Estimating SARS-CoV-2 Through Wastewater Surveillance Wastewater surveillance for the monitoring of SARS-CoV-2 may help identify potential variants of concern.
  Emerging Infectious Diseases, May 11, 2022
• Risk for Asymptomatic Household Transmission of C diff Recently hospitalized individuals may be potential asymptomatic C diff carriers. What is the risk for transmitting this infection to other household members?
  Emerging Infectious Diseases, May 06, 2022
• Suggestions for Successful SGLT2i Use in Glomerular Disease Findings from recent trials further support the benefits of SGLT2 inhibitors in the management of glomerular disease. This review provides guidance for successful implementation.
  Current Opinion in Nephrology and Hypertension, May 05, 2022
• Genomic Surveillance for SARS-CoV-2 Variants: Delta and Omicron This report summarizes the most recent CDC tracking of proportions of circulating and emerging variants of SARS-CoV-2.
  Morbidity & Mortality Weekly Report, May 04, 2022
• Rheumatoid Factor Positivity in ANCA-Associated Vasculitis What is the role of rheumatoid factor positivity in ANCA-associated vasculitis? A new study investigates.
  Rheumatology, May 04, 2022
• SARS-CoV-2 Infection Among Adults by Vaccination Status This study confirms that COVID-19 vaccination protects against severe COVID-19 caused by SARS-CoV-2 variants, including Omicron, especially for those who have received a booster.
  Morbidity & Mortality Weekly Report, April 29, 2022
• HbA1c Below the Reportable Range This case report highlights the limitations of using HbA1c as a diagnostic tool in patients with certain conditions, including, as in this patient, hemolytic anemia.
  Laboratory Medicine, April 29, 2022
• Gene Therapy for Recessive Dystrophic Epidermolysis Bullosa This review discusses the principles of gene therapy and its application to recessive dystrophic epidermolysis bullosa, the most debilitating variant of EB. Where does current research stand?
  The British Journal of Dermatology, April 26, 2022
• Preventing ALS: Insights From Other Neurodegenerative Diseases The authors apply what we know about prodromal clinical markers in other neurodegenerative diseases to amyotrophic lateral sclerosis. Might early therapeutic intervention--or prevention--be possible?
  Brain, April 21, 2022
• Elective Freezing of Embryos vs. Fresh Embryo Transfer in IVF Does electively freezing embryos, followed by frozen embryo transfer, result in a higher healthy baby rate compared with transferring fresh embryos?
  Human Reproduction, April 13, 2022
• Making the Case for Tailored Selection of Antiplatelet Therapy Recent studies have shown significant variability in response to clopidogrel. Should platelet function and genotyping for patients being treated with clopidogrel be the norm?
  European Heart Journal, April 07, 2022
• Spatiotemporal Analyses of 2 Circulating SARS-CoV-2 Variants What have we learned about the interplay between these two competing SARS-CoV-2 variants?
  Emerging Infectious Diseases, April 05, 2022
• Genetic Testing and Mortality in Breast or Ovarian Cancer Genetic testing could help determine mortality risk among newly diagnosed breast or ovarian cancer patients.
  Journal of the National Cancer Institute, March 23, 2022
• Pharmacologic Agents to Reverse Common Anticoagulants This review describes the various anticoagulants in use today, summarizing their characteristics and presenting a primer on how to appropriately reverse the effects of these drugs.
  Southern Medical Journal, March 23, 2022
• RNA-targeted Therapeutics in Preventive Cardiology Might RNA-targeted therapeutics aimed at reducing apoB-containing lipoproteins provide an entirely new strategy to prevent atherosclerotic cardiovascular diseases?
  European Heart Journal, March 21, 2022