Melanoma News

• Experts Urge Stopping Melanoma Trial Because of Failure and Harm New results from a phase 3 trial may shut the door on the addition of PD–1 or PD–ligand 1 inhibitors to the combination of BRAF and MEK inhibitors for the treatment of BRAF V600–mutated melanoma.
  Medscape Medical News, May 19, 2022
• ACMS 2022 Post-Mohs Bleeding Risk in Patients on Ibrutinib for CLL Studied Two studies evaluated the risk, with results indicating that holding the treatment before and after surgery helps reduce the risk for bleeding.
  Medscape Medical News, May 18, 2022
• Nearly 234,000 Cancer Cases Predicted in Canada This Year Although overall cancer rates are declining in Canada, the number of cases and deaths continue to climb due to population growth and an aging population.
  Medscape Medical News, May 13, 2022
• Study Hints at a Mechanism Behind Aggressive Melanoma A mutation in a gene involved in chromatin remodeling is associated with aggressive melanoma, suggest new data from preclinical research.
  Medscape Medical News, May 11, 2022
• Substantial Medical Debt, Bankruptcy Linked to Thyroid Cancer Compared to other cancers, patients with thyroid cancer may face more significant financial woes, including higher rates of bankruptcy.
  Medscape Medical News, May 09, 2022
• Pick Your Sunscreen Carefully: 75% Don't Pass Muster About 75% of more than 1850 sunscreen products evaluated offer inferior sun protection or have worrisome ingredients, according to the Environmental Working Group.
  WebMD Health News, May 06, 2022
• Q&A With Hubert (Hugh) Greenway, MD Anyone who practices Mohs micrographic surgery is likely to know the name Hugh Greenway, MD, the longtime head of Mohs and dermatologic surgery at Scripps Clinic in San Diego.
  Medscape Medical News, May 05, 2022
• Dermatopathologists May Perpetuate Melanoma Overdiagnosis, Despite Awareness Many dermatopathologists think atypical nevi, melanoma in situ and invasive melanoma are overdiagnosed, but awareness does not seem to change their behavior, a survey study found.
  Reuters Health Information, April 28, 2022
• High Suicide, Depression Risks for Patients With Cancer Two comprehensive studies provide strong evidence of the psychological impact cancer diagnoses and treatment can have on patients and reveal the need to ramp up mental health services.
  Medscape Medical News, April 25, 2022
• Age, Skin Cancer Risks for ICI-Induced Bullous Pemphigoid Bullous pemphigoid, a rare blistering skin condition, is seen in a small percentage of cancer patients treated with immune checkpoint inhibitors and may also be a tumor response marker.
  Medscape Medical News, April 21, 2022
• Overcoming Resistance to Radiotherapy for Brain Metastases Researchers have identified the molecular pathway that leads to resistance to whole brain radiotherapy, and also identified a potential therapeutic option.
  Medscape Medical News, April 21, 2022
• Adjuvant Pembrolizumab May Cut Recurrence, Mortality in Stage-II Melanoma Pembrolizumab as adjuvant therapy for patients with resected, high-risk stage-IIB or -IIC melanoma appears to reduce the risk of disease recurrence or death, according to interim analyses from the KEYNOTE-716 trial.
  Reuters Health Information, April 14, 2022
• Melanoma Screening Study Stokes Overdiagnosis Debate A new analysis showing significant increases in thin melanoma detections in the primary care setting reignites controversy over the pros and cons of regular melanoma screening.
  Medscape Medical News, April 14, 2022
• AAD 2022 PLA Test Brings Nuance to the Diagnosis of Early-Stage Melanoma Prospective randomized clinical trials are needed "to examine the role of genetic expression profiling in staging and managing patients," according to Caroline Kim, MD.
  Medscape Medical News, April 12, 2022
• SOCS 2022 Study Finds Biopsy Decisions, Diagnoses Differ by Skin Type The survey investigated the role of skin color in the assessment of neoplastic and inflammatory skin conditions and decisions to perform biopsy.
  Medscape Medical News, April 11, 2022
• 'Real-World' Increase in Biomarker Testing in NSCLC Real-world data from Spain suggest that biomarker testing for patients with advanced non–small cell lung cancer (NSCLC) is finally increasing.
  Medscape Medical News, April 08, 2022
• Little-known Offshoot of Hem/Onc Opens Up Career Development As awareness of vascular anomalies grows and research on effective treatments continues, this natural offshoot of hematology and oncology offers a fertile area for career development.
  Medscape Medical News, April 07, 2022
• Global Melanoma Incidence High and on the Rise If present trends continue, the incidence of new cases is predicted to increase by about 50% in 2040, according to the study's authors.
  Medscape Medical News, April 05, 2022
• Melanoma Increasing, but Is This Overdiagnosis? Melanoma incidence has been increasing in the United States over the last few decades. Some researchers argue that this is overdiagnosis, fueled by screening, especially among White patients.
  Medscape Medical News, March 29, 2022
• Preop Stereotactic Radiotherapy Tied to Improved Brain Metastases Outcomes In cancer patients with brain metastases, preoperative stereotactic radiotherapy is associated with improved outcomes compared to no SRT, a small trial shows.
  Reuters Health Information, March 28, 2022