Over-the-counter medications, food supplements, and other drugs may interact with antiretroviral therapy (ART) in people living with HIV and be harmful, an industry-sponsored clinical survey from Denmark reports.
"Our study confirms that polypharmacy and being on a protease inhibitor-based regimen increase the risk of potential drug-drug interactions (PDDIs) considerably and highlights the importance of questioning people living with HIV (PLWH) about dietary supplement intake," the authors, led by Michaela Tinggaard, MD, Copenhagen University Hospital, write in HIV Medicine.