A Rare Case of Status Epilepticus in a Patient Prescribed CBD

COMMENTARY

A Rare Case of Status Epilepticus in a Patient Prescribed CBD

Andrew N. Wilner, MD; Charles A. Szabo, MD

Disclosures

February 02, 2022

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This transcript has been edited for clarity.

Andrew N. Wilner, MD: Welcome to Medscape. I'm Dr Andrew Wilner reporting on the recent, virtually held American Epilepsy Society meeting.

With me today is Dr Charles Szabo, professor and chief of epilepsy at the University of Texas Health Science Center at San Antonio. Dr Szabo presented a very interesting case at this year's meeting about a patient on cannabidiol (CBD) adjunctive therapy. Welcome, Dr Szabo.

Charles A. Szabo, MD: Thank you very much for inviting me.

Wilner: Tell us about your case report.

Szabo: It's about a patient with a history of epilepsy since he was 7 years old. When we reported on him, he was 63 years old. His seizures had been very well controlled for a long time. He had mainly tonic and myoclonic seizures, often in his sleep or just upon awakening, and at times during the day too.

Suddenly, when he was 57 or 58, without any clear reason or cause, his seizures started to recur more frequently. He started having more serious seizures, such as convulsive seizures.

This prompted us to try different medications. We went through a number of different options before ending up with a very unusual regimen, even for epileptologists, consisting of

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