15 Need-to-Know Presentations From DDW 2021

COMMENTARY

15 Need-to-Know Presentations From DDW 2021

David A. Johnson, MD

Disclosures

May 26, 2021

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This transcript has been edited for clarity.

Hello. I'm Dr David Johnson, professor of medicine and chief of gastroenterology at Eastern Virginia Medical School in Norfolk, Virginia.

Although Digestive Disease Week 2021 was held virtually, that certainly didn't mean it was lacking in great science to report.

After going through this year's presentations, I wanted to give you my overview on those that I consider among the best, some with results that are actionable now and others whose impact may be felt farther away on the horizon.

Detecting Colorectal Cancer: How and Where

The first pair of studies come from Dr Joseph Anderson's group at Dartmouth College, using data from the New Hampshire Colonoscopy Registry.

The first study[1] compared the results of patients who underwent colonoscopy after having a positive fecal immunochemical test (FIT) or multitarget stool DNA (mt-sDNA) screening test, to those who underwent colonoscopy without such a preceding test. The investigators noted that patients with a positive mt-sDNA had a substantially higher yield of colorectal neoplasia than those with a positive FIT (67% vs 44%, respectively; P < .001).

The 2021 guidelines on colorectal cancer screening from the American College of Gastroenterology, which I recently reviewedactually recommend minimum acceptable thresholds for adenoma detection rates in FIT-positive populations of 45% in men and 35% in women.

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