This transcript has been edited for clarity.
Recently, I noticed something strange happening in my clinic. Most of my patients with type 1 diabetes are coming in with A1c levels below 7%—not slightly below 7%, but 5.7% to 6.5%. Many of these patients had had higher A1c levels for years and really struggled to bring them down.
When I think about it, there are two fundamental changes in the management of my patients with type 1 diabetes. Part of this is driven first by new concepts, specifically that of the ambulatory glucose profile, and second by new technology.
Time in Range
First, I'm going to talk about the concept that comes from patients wearing continuous glucose monitors, and that's the notion of time in range. An A1c result is a 3-month average, and it's kind of abstract. You can't tell based on an A1c of 7.5% whether a patient is high overnight and low in the afternoon. You only know what the average is.
The time in range tells you how much of the time a patient is in the range between 70 and 180 mg/dLYou know that a patient can have a good A1c of 6.5%, but be up and down and up and down. That's someone who may not feel like their diabetes is well controlled, and they may be suffering from frequent episodes of high and low blood sugars.
COMMENTARY
'Better Glycemic Control Than I've Ever Seen'
Anne L. Peters, MD
DisclosuresOctober 25, 2019
This transcript has been edited for clarity.
Recently, I noticed something strange happening in my clinic. Most of my patients with type 1 diabetes are coming in with A1c levels below 7%—not slightly below 7%, but 5.7% to 6.5%. Many of these patients had had higher A1c levels for years and really struggled to bring them down.
When I think about it, there are two fundamental changes in the management of my patients with type 1 diabetes. Part of this is driven first by new concepts, specifically that of the ambulatory glucose profile, and second by new technology.
Time in Range
First, I'm going to talk about the concept that comes from patients wearing continuous glucose monitors, and that's the notion of time in range. An A1c result is a 3-month average, and it's kind of abstract. You can't tell based on an A1c of 7.5% whether a patient is high overnight and low in the afternoon. You only know what the average is.
The time in range tells you how much of the time a patient is in the range between 70 and 180 mg/dLYou know that a patient can have a good A1c of 6.5%, but be up and down and up and down. That's someone who may not feel like their diabetes is well controlled, and they may be suffering from frequent episodes of high and low blood sugars.
Medscape Diabetes © 2019 WebMD, LLC
Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.
Cite this: Anne L. Peters. 'Better Glycemic Control Than I've Ever Seen' - Medscape - Oct 25, 2019.
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Authors and Disclosures
Authors and Disclosures
Author(s)
Anne L. Peters, MD
Professor, Department of Clinical Medicine, Keck School of Medicine; Director, University of Southern California Westside Center for Diabetes, University of Southern California, Los Angeles, California
Disclosure: Anne L. Peters, MD, has disclosed the following relevant financial relationships:
Serve(d) on the advisory board for: Abbott Diabetes Care; Becton Dickinson; Boehringer Ingelheim Pharmaceuticals, Inc.; Eli Lilly and Company; Lexicon Pharmaceuticals, Inc.; Livongo; Medscape; Merck & Co., Inc.; Novo Nordisk; Omada Health; OptumHealth; sanofi; Zafgen
Received research support from: Dexcom; MannKind Corporation; Astra Zeneca
Serve(d) as a member of a speakers bureau for: Novo Nordisk