McMaster EBM: Today, Melanoma Treatment

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McMaster EBM: Today, Lymph Node-Positive Melanoma Treatment

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This transcript has been edited for clarity.

Hello and welcome. I'm Dr George Lundberg and this is At Large at Medscape.

Anyone who practices medicine has a problem keeping up with a rapidly changing information landscape. What to read? What to trust?

Fortunately, free, trustworthy sources are available to help the reader sort it out. One such source is McMaster University in Hamilton, Ontario, which has been a focal point for evidence-based medicine (EBM) for decades, ever since that initiative was spearheaded there by the American, Dr David Sackett.

The open-access McMaster DynaMed Plus[1] includes a searchable collection of the best evidence from 500 top-rated medical journals and is presented in a format easy to read, comprehend, and upon which to clinically act. The database is continually updated and provides links for abstracts, ratings, and topics, and helpfully indicates whether the full-text link is or is not behind a paywall. I recommend that you get on their regular email list for Evidence Alerts.

Today we focus on malignant melanoma.[2] About 95,000 Americans are diagnosed with cutaneous melanoma each year. About 88,000 are cured; some 7000 die of the disease.

Surgery remains the principal treatment. Melanomas can spread by direct extension or by blood but typically metastasize via lymphatic channels.

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