Tofacitinib citrate (Xeljanz®; Xeljanz® XR)
For more on this Drug Safety Labeling Change, click here and here.
For full prescribing information, click here.
Updated Boxed Warning
Reported infections include:
Active tuberculosis, which may present with pulmonary or extrapulmonary disease. Patients should be tested for latent tuberculosis before XELJANZ/XELJANZ XR use and during therapy. Treatment for latent infection should be initiated prior to XELJANZ/XELJANZ XR use.
Invasive fungal infections, including cryptococcosis and pneumocystosis. Patients with invasive fungal infections may present with disseminated, rather than localized, disease.
Bacterial, viral, including herpes zoster, and other infections due to opportunistic pathogens.
Public Information from the FDA and Medscape
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Cite this: Drug Safety Warnings and Updates: October-December 2017 - Medscape - Feb 16, 2018.
