Rethinking the 'Cause' of Depression

COMMENTARY

Rethinking the 'Cause' of Depression

Stephen M. Strakowski, MD

Disclosures

June 23, 2017

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Hello. I'm Stephen M. Strakowski. I'm the founding chair of the new Department of Psychiatry at the new Dell Medical School at the University of Texas in Austin. Today I want to talk about depression and follow up on some implied discussion in a previous recording that we had a number of months ago.

Major Depression Overview

Major depression is among one of the most common ailments, and it may be the most common major medical problem once we eliminate viruses and so forth. About 7% of people are affected with depression annually, and there is somewhere around a 17% lifetime risk to perhaps as high as 1 in every 5 people.[1] Most people have either dealt with depression themselves or have family members or friends who've struggled with depression.

There are a number of studies that don't always agree, but in some studies it looks like depression is the leading cause of disability worldwide.[2]If not the leading cause, it's certainly one of the top two or three causes. There are higher rates in women, although there is some debate about that; it may be that it's just missed more often in men. It seems to be increased in people living in poverty and in stressful environments.

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