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The authors apply what we know about prodromal clinical markers in other neurodegenerative diseases to amyotrophic lateral sclerosis. Might early therapeutic intervention--or prevention--be possible?
This study indicates that the glutamate modulator riluzole slows decline of cerebral glucose metabolism in patients with Alzheimer disease, as measured by FDG-PET. Might it be an effective AD therapy?
This review provides an update on neurological manifestations of COVID-19 and examines what we know regarding the neuropathogenic mechanisms implicated in SARS-CoV-2 infection.